TRANSLATIONAL PHYSIOLOGY Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury
نویسندگان
چکیده
Michael T. Ganter, Lorraine B. Ware, Marybeth Howard, Jérémie Roux, Brandi Gartland, Michael A. Matthay, Monika Fleshner, and Jean-François Pittet Departments of Anesthesia, Surgery, and Medicine and the Cardiovascular Research Institute, University of California, San Francisco, California; Division of Allergy, Pulmonary, and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee; and Department of Integrative Physiology and Center for Neuroscience, University of Colorado, Boulder, Colorado
منابع مشابه
Extracellular heat shock protein 72 is a marker of the stress protein response in acute lung injury.
Previous studies have shown that heat shock protein 72 (Hsp72) is found in the extracellular space (eHsp72) and that eHsp72 has potent immunomodulatory effects. However, whether eHsp72 is present in the distal air spaces and whether eHsp72 could modulate removal of alveolar edema is unknown. The first objective was to determine whether Hsp72 is released within air spaces and whether Hsp72 level...
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تاریخ انتشار 2006